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抑制剂 & 化合物

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重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T39371 LKY-047

LKY-047, a derivative of Decursin, is a highly effective and specific reversible competitive inhibitor of cytochrome P45022J2 (CYP2J2), with an IC 50 value of 1.7 μM. LKY-047 does not display inhibitory activity against other human P450 enzymes including CYPs 1A2, 2A6, 2B6, 2C8, 2C9, 2C19, 2D6, 2E1, and 3A.

化合物

LKY-047
Cat.No: T39371
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPH-02618 CYP2E1 Protein, Mouse, Recombinant (His)

Cyp2e1,Cytochrome P450 2E1

Mouse E. coli
A cytochrome P450 monooxygenase involved in the metabolism of fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds. Hydroxylates fatty acids specifically at the omega-1 position displaying the highest catalytic activity for saturated fatty acids. May be invo...

重组蛋白

CYP2E1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02618
Species: Mouse
Expression System: E. coli
TargetMol Loading
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